BDBM18444 4-[benzene(methyl)sulfonamido]-N-(1,3-thiazol-2-yl)benzamide::Sulfonamide analogue, 24::cid_1309992

SMILES CN(c1ccc(cc1)C(=O)Nc1nccs1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=LJZYYSIPPKMYER-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18444   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18444(4-[benzene(methyl)sulfonamido]-N-(1,3-thiazol-2-yl...)
Affinity DataKi:  2.34E+4nM ΔG°:  -6.23kcal/mole IC50:  3.44E+4nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM18444(4-[benzene(methyl)sulfonamido]-N-(1,3-thiazol-2-yl...)
Affinity DataIC50:  4.69E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay