BDBM18448 2-({4-[(3-methylphenyl)amino]-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-yl}amino)ethan-1-ol::Triazine compound, 27::triazine scaffold, 26

SMILES Cc1cccc(Nc2nc(NCCO)nc(n2)N2CCCC2)c1

InChI Key InChIKey=DSLSXSSYABXXSB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18448   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18448(2-({4-[(3-methylphenyl)amino]-6-(pyrrolidin-1-yl)-...)
Affinity DataKi:  2.78E+3nM ΔG°:  -7.47kcal/mole IC50:  4.31E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Nih

LigandPNGBDBM18448(2-({4-[(3-methylphenyl)amino]-6-(pyrrolidin-1-yl)-...)
Affinity DataIC50:  6.19E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed