BDBM18524 6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::CHEMBL436784::LGD2226
SMILES FC(F)(F)CN(CC(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F
InChI Key InChIKey=ULBPQWIGZUGPHU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 18524
Affinity DataKi: 4.60nM ΔG°: -11.8kcal/mole EC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Modulation of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human Androgen receptorMore data for this Ligand-Target Pair