BDBM18552 7-[(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::alkylamino-2-quinolinone, 9l

SMILES FC(F)(F)CNc1ccc2c(cc(=O)[nH]c2c1)C(F)(F)F

InChI Key InChIKey=CCHQAGTYRRITNM-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18552   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18552(7-[(2,2,2-trifluoroethyl)amino]-4-(trifluoromethyl...)
Affinity DataKi:  15nM ΔG°:  -11.1kcal/mole IC50:  21nM EC50:  905nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed