BDBM188520 ISOX-DUAL

SMILES CN(C)CCCOc1ccc(CCc2nc3cc(ccc3n2CCN2CCOCC2)-c2c(C)noc2C)cc1

InChI Key InChIKey=HCDQWCDANVEBQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 188520   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188520(ISOX-DUAL)
Affinity DataIC50:  1.50E+3nMAssay Description:The assay used a Cy5 dye-labeled BRD inhibitor PFI-411FP. The synthesis of the probe and the procedure for the assay was reported recently (Hett et a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Pfizer

LigandPNGBDBM188520(ISOX-DUAL)
Affinity DataIC50:  650nMAssay Description:The assay used His-tagged CBP protein, biotinylated histone H4, and detection reagents europium-labeled streptavidin and anti-6His antibody labeled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed