BDBM190235 US9174999, Table 1, Compound 3::US9174999, Table 1, Compound 4

SMILES OC1(O)CCN2C(=N)N[C@@H](COC(=O)NC3CCCCC3)[C@@H]3NC(=N)N[C@]123

InChI Key InChIKey=DMNGGGFGCGRWLA-MMPTUQATSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 190235   

TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM190235(US9174999, Table 1, Compound 3 | US9174999, Table ...)
Affinity DataIC50:  230nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 4 subunit alpha [M1240A](Rattus norvegicus (Rat))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM190235(US9174999, Table 1, Compound 3 | US9174999, Table ...)
Affinity DataIC50:  1.00E+3nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 4 subunit alpha [I757A](Rattus norvegicus (Rat))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM190235(US9174999, Table 1, Compound 3 | US9174999, Table ...)
Affinity DataIC50:  700nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM190235(US9174999, Table 1, Compound 3 | US9174999, Table ...)
Affinity DataIC50:  6.00E+5nMAssay Description:In initial studies, we designed a set of molecules with branching at the nitrogen of the carbamate side chain as well as the carbon adjacent to the n...More data for this Ligand-Target Pair
In DepthDetails US Patent