BDBM190642 US9181230, 48::US9181230, 50

SMILES FC(F)(F)c1cnc2[nH]c3ccc(cc3c2c1)[C@@H]1CNCCO1

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 190642   

TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM190642(US9181230, 48 | US9181230, 50)
Affinity DataKi:  8.10nM ΔG°:  -11.5kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM190642(US9181230, 48 | US9181230, 50)
Affinity DataKi:  8.20nM ΔG°:  -11.5kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM190642(US9181230, 48 | US9181230, 50)
Affinity DataKi:  30.3nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM190642(US9181230, 48 | US9181230, 50)
Affinity DataKi:  63.9nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...More data for this Ligand-Target Pair
In DepthDetails US Patent