BDBM192355 US9187462, I-35

SMILES C[C@@H]1CC[C@@H](N1)[C@@H](NC(=O)c1ccc2cnc(NC3CCOCC3)nc2c1)c1ccc(Cl)c(F)c1

InChI Key InChIKey=BJQJOYNOELTEHJ-CHVDNLQBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192355   

TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM192355(US9187462, I-35)
Affinity DataIC50:  2nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent