BDBM196728 (r)-2-(((2,6-difluorophenyl)amino)methyl)-5-(4-fluorophenyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one::US9676782, 72

SMILES C[C@@H]1CN(C(=O)c2cc(CNc3c(F)cccc3F)nn12)c1ccc(F)cc1

InChI Key InChIKey=FZPRUISWUIXPMH-GFCCVEGCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196728   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM196728((r)-2-(((2,6-difluorophenyl)amino)methyl)-5-(4-flu...)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:Gα15/TREx cells stably expressing rat mGlu3 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University

US Patent
LigandPNGBDBM196728((r)-2-(((2,6-difluorophenyl)amino)methyl)-5-(4-flu...)
Affinity DataIC50:  1.92E+3nMT: 2°CAssay Description:HEK 293A cells stably expressing rat mGlu5 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 μL of assay m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent