BDBM19850 (1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-[2-(4-fluorophenyl)phenyl]cyclohexane-1-carboxamide::Cyclohexanecarboxamide derivative, rac-34b::racemic mixture

SMILES Fc1ccc(cc1)-c1ccccc1[C@@H]1CCC(F)(F)C[C@H]1C(=O)NCC#N

InChI Key InChIKey=ZVLQAJSIMPOGGG-RBUKOAKNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19850   

TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19850((1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-[2-(4-fluor...)
Affinity DataIC50:  19nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19850((1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-[2-(4-fluor...)
Affinity DataIC50:  36nMAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed