BDBM19909 (1R,2R)-N-(cyanomethyl)-5,5-difluoro-2-{1-methyl-4-[4-(methylsulfanyl)phenyl]-1H-pyrazol-3-yl}cyclohexane-1-carboxamide::CHEMBL492654::beta-substituted cyclohexanecarboxamide, 10
SMILES CSc1ccc(cc1)-c1cn(C)nc1[C@@H]1CCC(F)(F)C[C@H]1C(=O)NCC#N
InChI Key InChIKey=HKMXKYIDIHEDMF-HZPDHXFCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 19909
Affinity DataIC50: 0.400nM EC50: 41nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nM EC50: 41nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair