BDBM19969 (2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0.0^{2,6}]trideca-1(13),9,11-trien-12-ol::SERBA-2

SMILES Oc1ccc(cc1)[C@H]1Oc2ccc(O)cc2[C@H]2CCC[C@@H]12

InChI Key InChIKey=XIESSJVMWNJCGZ-HDMKZQKVSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19969   

TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  1.54nM ΔG°:  -11.9kcal/mole EC50:  3.61nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  1.54nM ΔG°:  -11.9kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  14.5nM ΔG°:  -10.6kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM19969((2S,6R,7S)-7-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0...)
Affinity DataKi:  14.5nM ΔG°:  -10.6kcal/mole EC50:  32.5nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed