BDBM199986 US9227959, Reference Compound 2, Ex. 46
SMILES CC1(C)CCCN(C1)C(=O)c1ncc(cn1)C#Cc1ccccc1
InChI Key InChIKey=UCYCJYJSMSDBIV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 199986
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataKi: 315nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was
transiently transfected into EBNA cells using a procedure described by
Schlaeger ...More data for this Ligand-Target Pair
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataEC50: 50nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair