BDBM200305 US9226927, 14
SMILES Cc1nc(CS(=O)(=O)CC[C@@H]2OCC[C@@]3(C2COc2c(F)ccc(F)c32)S(=O)(=O)c2ccc(Cl)cc2)no1
InChI Key InChIKey=ZYQZOZIQPXMFMN-OUSZHMKWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 200305
Affinity DataIC50: 5.80nMpH: 7.0 T: 2°CAssay Description:To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...More data for this Ligand-Target Pair