BDBM202086 US9233983, B-5
SMILES OCc1c(cccc1-c1ncnc2[nH]c(cc12)-c1ccc(CN2CCOCC2)cc1)N1CCOc2cc(ccc2C1=O)C1CC1
InChI Key InChIKey=PSIWUKBLYARZHY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 202086
Affinity DataIC50: 8nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase
assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based
on t...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair