BDBM202200 US9233983, P-15
SMILES CC1(O)CN(C1)C(=O)N1CCC(=CC1)c1cc2c(ccnc2[nH]1)-c1cccc(N2CCOc3cc(cc(F)c3C2=O)C2CC2)c1CO
InChI Key InChIKey=OJNINYKJMHYTKF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 202200
Affinity DataIC50: 1nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase
assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based
on t...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair