BDBM202402 BDBM202403::US9238644, 9

SMILES NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2ccc(nc2)C(F)(F)F)ncc1Cl

InChI Key InChIKey=MZYDUEWRHJEHIO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 202402   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202402(BDBM202403 | US9238644, 9)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:Adult human umbilical vein endothelial cells (HUVEC) (Cat# CC-2519, Lonza) were seeded into clear-bottom, TC treated 12 well plates (Cat #665180, G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202402(BDBM202403 | US9238644, 9)
Affinity DataIC50:  75nMpH: 7.2 T: 2°CAssay Description:Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202402(BDBM202403 | US9238644, 9)
Affinity DataIC50:  92nMpH: 7.4Assay Description:A biotin labelled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Cancer Therapeutics Crc Pty

US Patent
LigandPNGBDBM202402(BDBM202403 | US9238644, 9)
Affinity DataIC50:  26nMpH: 7.4Assay Description:A biotin labelled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent