BDBM205176 US9249114, A9

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2sc(nc2C(N)=O)-c2ccnc(c2)C#N)CC1

InChI Key InChIKey=QXLKSIFNOSQVJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205176   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM205176(US9249114, A9)
Affinity DataIC50:  740nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed either as 384-well Flashplate assay (for e.g. Topcount measurement). 1 nM IKKε, 800 nM biotinylated IκB&a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM205176(US9249114, A9)
Affinity DataIC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well Flashplate assay assay (for e.g. Topcount measurement. 0.6 nM TANK binding kinase (TBK1), 800 nM biotinyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent