BDBM210941 2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(m-tolyl)-1H-pyrrol-1-yl)benzamide (5c)::US10975030, Compound 5c

SMILES Cc1cccc(c1)-c1cccn1-c1ccc(C(N)=O)c(NC2CCC(O)CC2)c1

InChI Key InChIKey=UTFAYPZPLVXYRJ-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 210941   

TargetEndoplasmin(Homo sapiens (Human))
The University of Kansas

LigandPNGBDBM210941(2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(m-tol...)
Affinity DataKd:  9.43E+3nMpH: 7.3Assay Description:Assay buffer (25 μL, 20 mM HEPES at pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg mL−1 BGG) was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM210941(2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(m-tol...)
Affinity DataKd: >1.00E+5nMAssay Description:Assay buffer (25 μL, 20 mM HEPES pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg/mL BGG) was added to 96-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM210941(2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(m-tol...)
Affinity DataKd: >1.00E+5nMpH: 7.3Assay Description:Assay buffer (25 μL, 20 mM HEPES at pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg mL−1 BGG) was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed