BDBM212104 US9290485, 136

SMILES Cc1nc(N)cc(OCC(=O)C(C)(C)C)c1CNC(=O)c1cn(Cc2ccccc2)nn1

InChI Key InChIKey=FWRKGUCVNZBFQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212104   

TargetPlasma kallikrein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM212104(US9290485, 136)
Affinity DataIC50:  24nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in â¿¿assay bufferâ¿¿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent