BDBM21296 1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indol-6-ol::Tetrahydropyranyl-methyl analogue, 17

SMILES CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(O)ccc23)C1(C)C

InChI Key InChIKey=YNHUJCRFFWWTHM-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21296   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21296(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21296(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataKi:  8.5nM EC50:  18.5nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21296(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataKi:  2.95E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21296(1-(oxan-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopr...)
Affinity DataKi: >3.00E+3nM ΔG°: >-7.66kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed