BDBM213079 US9278960, 6-26::US9663506, Example 6-26

SMILES Cn1cc(cn1)-c1cc(nc2cc(Cc3cc(nc(c3)C(F)(F)F)C3CC3)ccc12)C(N)=O

InChI Key InChIKey=KIHRXNGLVNMIHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 213079   

LigandPNGBDBM213079(US9278960, 6-26 | US9663506, Example 6-26)
Affinity DataIC50:  12nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213079(US9278960, 6-26 | US9663506, Example 6-26)
Affinity DataIC50:  12nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM213079(US9278960, 6-26 | US9663506, Example 6-26)
Affinity DataIC50:  12nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent