BDBM2156 1-(5-chloropyridin-2-yl)-3-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]thiourea::LY300046HCl Analog 42::N-[2-(N-Phthalimidyl)ethyl]-N-[2-(5-chloropyridyl)]-thiourea::PETT deriv.
SMILES Clc1ccc(NC(=S)NCCN2C(=O)c3ccccc3C2=O)nc1
InChI Key InChIKey=HDMIEYWFCFYJJE-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2156
Affinity DataIC50: 1nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 280nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair