BDBM21653 (2S)-2-[(2R)-2-[(1R)-2,3-dihydro-1H-inden-1-yl]-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanoic acid::CHEMBL285490::Mercaptoacyl amino acid compound, 13b
SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CS)[C@H]1CCc2ccccc12
InChI Key InChIKey=AXECOZSOSVNVEZ-ZVDOUQERSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 21653
Affinity DataKi: 0.700nM ΔG°: -13.0kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:In vitro inhibition of Neutral endopeptidase.More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:ECE activity was performed in black 96-well microplates with recombinant human ECE-1c (hECE-1c). The hECE-1c was preincubated with or without increa...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:In vitro inhibition of endothelin converting enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Specific activity of ACE was assayed in black 96-well microplates with or without various concentrations of inhibitors. N-Cbz-Phe-His-Leu was added, ...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme.More data for this Ligand-Target Pair