BDBM21691 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid::Nalidixic Acid::Nalidixin::NegGram::Nevigramon::US9138393, Nalidixic acid::US9144538, Nalidixic acid

SMILES CCn1cc(C(O)=O)c(=O)c2ccc(C)nc12

InChI Key InChIKey=MHWLWQUZZRMNGJ-UHFFFAOYSA-N

Data  19 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21691   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Henan University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM21691(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridi...)
Affinity DataIC50:  7.32E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase super-coiling activity using pBR322 DNA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed