BDBM22001 5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methylpropyl)-6-(naphthalen-1-ylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione::Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 3

SMILES CC(C)Cn1c2sc(Cc3cccc4ccccc34)c(SCCCO)c2c(=O)n(C)c1=O

InChI Key InChIKey=SJZYZYMKFRJDEE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22001   

TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM22001(5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...)
Affinity DataKi:  0.275nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM22001(5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...)
Affinity DataKi:  0.280nM ΔG°:  -12.9kcal/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM22001(5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...)
Affinity DataKi:  0.302nMAssay Description:Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed