BDBM223255 2-(5-((3-Chloro-2,4-difluorobenzyl)(cyclopropylmethyl)amino)-3-methoxypicolinoyl)cyclopropanecarboxylic acid::US20160326143, 30::US9657001, 30

SMILES COc1cc(cnc1C(=O)C1CC1C(O)=O)N(CC1CC1)Cc1ccc(F)c(Cl)c1F

InChI Key InChIKey=LBXDHNIMLOJYEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223255   

TargetLeukotriene C4 synthase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM223255(2-(5-((3-Chloro-2,4-difluorobenzyl)(cyclopropylmet...)
Affinity DataIC50:  152nMAssay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM223255(2-(5-((3-Chloro-2,4-difluorobenzyl)(cyclopropylmet...)
Affinity DataIC50:  152nMpH: 7.8Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent