BDBM225267 2-((5-Chloro-2-hydroxyphenyl)amino)-N-(3-(morpholinosulfonyl)phenyl)propanamide (7c)

SMILES CC(Nc1cc(Cl)ccc1O)C(=O)Nc1cccc(c1)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=BVQMYYOWBKUYQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225267   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM225267(2-((5-Chloro-2-hydroxyphenyl)amino)-N-(3-(morpholi...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human LSD1 (158 to end residues) expressed in Escherichia coli preincubated for 15 mins followed by H3K4me2 peptide addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM225267(2-((5-Chloro-2-hydroxyphenyl)amino)-N-(3-(morpholi...)
Affinity DataIC50:  1.30E+4nMpH: 7.5 T: 2°CAssay Description:The LSD1 screening biochemical assay was performed by Shanghai ChemPartner Co. Ltd and the detailed protocol was shown as followed. The AlphaLISA ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed