BDBM22536 1-[3-(1H-imidazol-4-ylmethyl)phenyl]-3,3-dimethylbutan-1-one::4-Benzyl-1H-imidazole derivative, 17

SMILES CC(C)(C)CC(=O)c1cccc(Cc2cnc[nH]2)c1

InChI Key InChIKey=SHQNNJIERWMYHK-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22536   

TargetHistamine H4 receptor(Homo sapiens (Human))
Vu University Amsterdam

LigandPNGBDBM22536(1-[3-(1H-imidazol-4-ylmethyl)phenyl]-3,3-dimethylb...)
Affinity DataKi:  6nM ΔG°:  -11.2kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH4R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Vu University Amsterdam

LigandPNGBDBM22536(1-[3-(1H-imidazol-4-ylmethyl)phenyl]-3,3-dimethylb...)
Affinity DataKi:  32nM ΔG°:  -10.2kcal/mole EC50:  79nMpH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed