BDBM22883 CHEMBL12344::Dimaprit::[3-(carbamimidoylsulfanyl)propyl]dimethylamine

SMILES CN(C)CCCSC(N)=N

InChI Key InChIKey=OLHQOJYVQUNWPL-UHFFFAOYSA-N

Data  11 KI  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22883   

TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM22883(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Affinity DataKi:  316nM ΔG°:  -9.22kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed