BDBM2340 Pyrrolyl Aryl Sulfone (PAS) 8f::n-Propyl 1-[(2-Amino-5-chlorophenyl)sulfonyl]-1Hpyrrole-2-carboxylate::propyl 1-[(2-amino-5-chlorobenzene)sulfonyl]-1H-pyrrole-2-carboxylate

SMILES CCCOC(=O)c1cccn1S(=O)(=O)c1cc(Cl)ccc1N

InChI Key InChIKey=SMOKWPAQTJHXEP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2340   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Universita Di Roma

LigandPNGBDBM2340(Pyrrolyl Aryl Sulfone (PAS) 8f | n-Propyl 1-[(2-Am...)
Affinity DataIC50:  400nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Universita Di Roma

LigandPNGBDBM2340(Pyrrolyl Aryl Sulfone (PAS) 8f | n-Propyl 1-[(2-Am...)
Affinity DataIC50:  1.00E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Universita Di Roma

LigandPNGBDBM2340(Pyrrolyl Aryl Sulfone (PAS) 8f | n-Propyl 1-[(2-Am...)
Affinity DataIC50:  5.00E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed