BDBM234954 4-(2-((4-(4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)-n-(cyanomethyl)benzamide::US9556148, 17
SMILES O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCC(CC2)N2CC3CC(C2)O3)n1
InChI Key InChIKey=MCYIJFIRVPYHPF-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 234954
Affinity DataIC50: 13nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair