BDBM23517 2-[2-(4-methoxyphenoxy)acetamido]benzoic acid::Biaryl Anthranilide Analogue, 1a::CHEMBL228244

SMILES COc1ccc(OCC(=O)Nc2ccccc2C(O)=O)cc1

InChI Key InChIKey=JHCUZGSREIUIPD-UHFFFAOYSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23517   

TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23517(2-[2-(4-methoxyphenoxy)acetamido]benzoic acid | Bi...)
Affinity DataIC50: >2.50E+3nM EC50:  6.00E+3nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23517(2-[2-(4-methoxyphenoxy)acetamido]benzoic acid | Bi...)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23517(2-[2-(4-methoxyphenoxy)acetamido]benzoic acid | Bi...)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM23517(2-[2-(4-methoxyphenoxy)acetamido]benzoic acid | Bi...)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at human GPR109A receptor expressed in CHO-K1 cells by [35S]GTPgammaS guanine nucleotide exchange assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed