BDBM236493 US10988505, Comparative #2::US9365853, 4

SMILES C[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=FQROGHZFOUYCQG-OBJOEFQTSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 236493   

TargetSuppressor of tumorigenicity 14 protein [596-855](Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM236493(US10988505, Comparative #2 | US9365853, 4)
Affinity DataKi:  0.0880nM ΔG°:  -13.7kcal/molepH: 7.4 T: 2°CAssay Description:Enzymatic assays were performed in the following reaction buffer: 50 mM HEPES, pH 7.4 containing 500 μg/ml bovine serum albumin. Enzyme activiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransmembrane protease serine 6(Homo sapiens (Human))
SociÉTÉ

US Patent
LigandPNGBDBM236493(US10988505, Comparative #2 | US9365853, 4)
Affinity DataKi:  0.0880nMAssay Description:Enzymatic assays and Ki determination were performed at room temperature in an assay buffer containing 50 mM Tris-HCl, 150 mM NaCl and 500 μg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHemagglutinin(Influenza A virus (strain A/X-31 H3N2))
SociÉTÉ

US Patent
LigandPNGBDBM236493(US10988505, Comparative #2 | US9365853, 4)
Affinity DataEC50:  5.69E+3nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent