BDBM238185 US9394303, 57
SMILES Cc1nn(Cc2ccc(Oc3cc(C)c(Cl)c(C)c3)cc2)c2nc(cc(C(O)=O)c12)-c1ccco1
InChI Key InChIKey=LTAWGVCXLNOXJX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 238185
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 130nM ΔG°: -9.39kcal/mole IC50: 670nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Mus musculus (Mouse))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 1.95E+3nM ΔG°: -7.78kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nM ΔG°: >-7.23kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair