BDBM238185 US9394303, 57

SMILES Cc1nn(Cc2ccc(Oc3cc(C)c(Cl)c(C)c3)cc2)c2nc(cc(C(O)=O)c12)-c1ccco1

InChI Key InChIKey=LTAWGVCXLNOXJX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238185   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238185(US9394303, 57)
Affinity DataKi:  130nM ΔG°:  -9.39kcal/mole IC50:  670nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238185(US9394303, 57)
Affinity DataKi:  1.95E+3nM ΔG°:  -7.78kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Mus musculus (Mouse))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238185(US9394303, 57)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.23kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In DepthDetails US Patent