BDBM238326 US9394273, 15

SMILES OC(Cc1ccc2ccsc2c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O

InChI Key InChIKey=VJHDOMGAUGDZBU-JWZNCFRCSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 238326   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataKi:  41nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataKi: >1.00E+4nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataEC50:  0.5nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataEC50: <10nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataEC50:  67nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent