BDBM238624 US9394297, 284

SMILES CC(C)(C)Nc1nc2c(cccc2[nH]c1=O)-c1cc2c(CCNC2=O)[nH]1

InChI Key InChIKey=QVQNZMJSTKPJKL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238624   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238624(US9394297, 284)
Affinity DataIC50:  1.20nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238624(US9394297, 284)
Affinity DataIC50:  0.0378nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238624(US9394297, 284)
Affinity DataIC50:  0.0282nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent