BDBM24106 2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline::tetrahydroisoquinoline (THIQ), 11

SMILES CN1CC(c2ccccc2)c2ccc(C)c(C)c2C1

InChI Key InChIKey=KJSYAMNHDJSTMY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24106   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM24106(2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataKi:  135nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM24106(2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataKi:  227nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM24106(2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataKi:  1.75E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM24106(2,7,8-trimethyl-4-phenyl-1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50:  1.84E+4nMpH: 7.0 T: 2°CAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed