BDBM241110 US9409895, 21::US9630945, 21

SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CCNC(=O)c3c[nH]c(=O)o3)CC2)c1

InChI Key InChIKey=BLGXOKQLEAWQMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 241110   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM241110(US9409895, 21 | US9630945, 21)
Affinity DataIC50:  106nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM241110(US9409895, 21 | US9630945, 21)
Affinity DataIC50:  86nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtaxin-2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM241110(US9409895, 21 | US9630945, 21)
Affinity DataIC50:  106nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent