BDBM241943 US9422333, I-23
SMILES CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@H](CNC(=O)C=C)NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(OC(=O)C(F)(F)F)C(=O)NC1CC1
InChI Key InChIKey=UABMAUQOFZTIIT-QQWMEIISSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 241943
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: >111nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
TargetGenome polyprotein [1027-1207,A156S](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 412nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 463nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 508nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
TargetGenome polyprotein [1027-1207,A156T](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 985nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair