BDBM24775 2-methoxy-1,4-dihydronaphthalene-1,4-dione::2-methoxy-1,4-dihydronaphthalene-1,4-dione (5c)::2-methoxy-1,4-naphthoquinone, 2::CHEMBL106562

SMILES COC1=CC(=O)c2ccccc2C1=O

InChI Key InChIKey=OBGBGHKYJAOXRR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 24775   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50:  720nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50:  2.04E+4nMAssay Description:The protocol for measuring IC50 values for the inhibition of MAO-A and MAO-B has been reported in detail in a recent publication (26). The recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase(Homo sapiens (Human))
North-West University

LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50:  2.48E+4nMAssay Description:The protocol for measuring IC50 values for the inhibition of MAO-A and MAO-B has been reported in detail in a recent publication (26). The recombinan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
University Of Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of SET7 (unknown origin) using biotinylated histone polypeptide as substrate in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 1(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM24775(2-methoxy-1,4-dihydronaphthalene-1,4-dione | 2-met...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibitory activity against HRV 3Cpro using HPLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed