BDBM249466 US10072016, Compound 65::US10407433, Compound 65::US10913746, Compound 65::US11649240, Compound 65::US9434727, 65::US9777010, Compound 65

SMILES Fc1cccc(C2CCN(CC2)C(=O)c2nnc3ccc(cn23)C#N)c1C(F)(F)F

InChI Key InChIKey=TZIIUZZREBUIBM-UHFFFAOYSA-N

Data  1 KI  44 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 249466   

TargetRetinol-binding protein 4(Homo sapiens (Human))
Columbia University

US Patent
LigandPNGBDBM249466(US10072016, Compound 65 | US10407433, Compound 65 ...)
Affinity DataIC50:  4.13nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinol-binding protein 4(Homo sapiens (Human))
Columbia University

US Patent
LigandPNGBDBM249466(US10072016, Compound 65 | US10407433, Compound 65 ...)
Affinity DataIC50:  5.36nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinol-binding protein 4(Homo sapiens (Human))
Columbia University

US Patent
LigandPNGBDBM249466(US10072016, Compound 65 | US10407433, Compound 65 ...)
Affinity DataIC50:  5.36nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinol-binding protein 4(Homo sapiens (Human))
Columbia University

US Patent
LigandPNGBDBM249466(US10072016, Compound 65 | US10407433, Compound 65 ...)
Affinity DataIC50:  5.36nMAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent