BDBM250506 US9469627, 1

SMILES CC(C)(O)c1nc(no1)-c1cccc(CNC(=O)c2cnc(nc2)-c2ccccn2)c1

InChI Key InChIKey=VJCLAPUACUQZOV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250506   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM250506(US9469627, 1)
Affinity DataIC50:  12nMpH: 7.4Assay Description:I. Assay Solutions a. Preparation of 0.1M K2HPO4/KH2PO4 buffer (pH 7.4) Prepare 0.1 M KH2PO4 from 1M KH2PO4 (Sigma, Cat# P-8709) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM250506(US9469627, 1)
Affinity DataIC50:  12nMAssay Description:Inhibition of HPGDS (unknown origin) assessed as reduction in reduction in LPS-induced PGD2 level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM250506(US9469627, 1)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of HPGDS (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed