BDBM25058 (5Z)-5-[(3-hydroxy-5-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::Compound I, rhodanine

SMILES COc1cc(O)cc(\C=C2/SC(=S)NC2=O)c1

InChI Key InChIKey=LSVTZBNOOSOZLV-WTKPLQERSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25058   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
The University Of Jordan

Curated by ChEMBL
LigandPNGBDBM25058((5Z)-5-[(3-hydroxy-5-methoxyphenyl)methylidene]-2-...)
Affinity DataIC50:  328nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25058((5Z)-5-[(3-hydroxy-5-methoxyphenyl)methylidene]-2-...)
Affinity DataIC50:  77.7nMpH: 7.4 T: 2°CAssay Description:PI3Kgamma activity was assessed by incubation of baculoviral co-expressed regulatory and catalytic subunits (p101 and p110) with lipid micelles prepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed