BDBM251475 US9452998, 24

SMILES CC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C#N

InChI Key InChIKey=NQESDTBKBPAEPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251475   

TargetProtein kinase C theta type(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM251475(US9452998, 24)
Affinity DataIC50:  1.20nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM251475(US9452998, 24)
Affinity DataIC50:  0.400nMpH: 7.4Assay Description:The compounds of formula I were tested for their activity on different PKC isoforms according to a published method (D. Geiges et al. Biochem. Pharma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent