BDBM25342 N-methyl-pyrimidinone derivative, 18

SMILES COc1cccc(CNC(=O)c2nc(n(C)c(=O)c2O)C(C)(C)NC(=O)C(=O)N(C)C)c1OC

InChI Key InChIKey=HIUQYSIFZDXRMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25342   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Research Laboratories

LigandPNGBDBM25342(N-methyl-pyrimidinone derivative, 18)
Affinity DataIC50:  21nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed