BDBM25345 N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-2-[2-(pyridin-2-ylformamido)propan-2-yl]-1,6-dihydropyrimidine-4-carboxamide::N-methyl-pyrimidinone derivative, 21

SMILES Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C(C)(C)NC(=O)c1ccccn1

InChI Key InChIKey=AYYZVIZCPBKXCO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25345   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Research Laboratories

LigandPNGBDBM25345(N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-ox...)
Affinity DataIC50:  20nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed