BDBM25870 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro

SMILES CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1

InChI Key InChIKey=WSEQXVZVJXJVFP-UHFFFAOYSA-N

Data  130 KI  25 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25870   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  6.19E+3nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [3H]-ni...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)
Affinity DataKi:  1.65E+4nMAssay Description:In vitro binding affinity of the compound was determined against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 radioligan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank