BDBM259239 US9499502, Table A: Entry 20
SMILES CC1(C)C(=N)N[C@@](C)(CS1(=O)=O)c1nc(N)ccc1F
InChI Key InChIKey=DCJNEELRLJWWNF-LBPRGKRZSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259239
Affinity DataKi: 4.60E+3nM ΔG°: -7.40kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nM ΔG°: -7.22kcal/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair