BDBM26399 14-fluoro-6-(piperazin-1-yl)-3,5-diazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-4-amine::2,4-diamino-5,6-disubstituted pyrimidine, 13

SMILES Nc1nc(N2CCNCC2)c2CCCc3ccc(F)cc3-c2n1

InChI Key InChIKey=ZKRHBPHZPPNOHI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26399   

TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM26399(14-fluoro-6-(piperazin-1-yl)-3,5-diazatricyclo[9.4...)
Affinity DataKi:  1.45nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26399(14-fluoro-6-(piperazin-1-yl)-3,5-diazatricyclo[9.4...)
Affinity DataKi:  5.10nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed